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Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors

We have used the hematopoietic system as a model to investigate whether acute myeloid leukemia arises exclusively from self-renewing stem cells or also from short-lived myeloid progenitors. When transduced with a leukemogenic MLL fusion gene, prospectively isolated stem cells and myeloid progenitor...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Cozzio, Antonio, Passegué, Emmanuelle, Ayton, Paul M., Karsunky, Holger, Cleary, Michael L., Weissman, Irving L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Cold Spring Harbor Laboratory Press 2003
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC305255/
https://ncbi.nlm.nih.gov/pubmed/14701873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1143403
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