Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors

We have used the hematopoietic system as a model to investigate whether acute myeloid leukemia arises exclusively from self-renewing stem cells or also from short-lived myeloid progenitors. When transduced with a leukemogenic MLL fusion gene, prospectively isolated stem cells and myeloid progenitor...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genes Dev
Main Authors: Cozzio, Antonio, Passegué, Emmanuelle, Ayton, Paul M., Karsunky, Holger, Cleary, Michael L., Weissman, Irving L.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2003
Teme:
Research Communications
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305255/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14701873/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1143403
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