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Vascular CD39/ENTPD1 Directly Promotes Tumor Cell Growth by Scavenging Extracellular Adenosine Triphosphate

Extracellular adenosine triphosphate (ATP) is known to boost immune responses in the tumor microenvironment but might also contribute directly to cancer cell death. CD39/ENTPD1 is the dominant ectonucleotidase expressed by endothelial cells and regulatory T cells and catalyzes the sequential hydroly...

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Autori principali: Feng, Lili, Sun, Xiaofeng, Csizmadia, Eva, Han, Lihui, Bian, Shu, Murakami, Takashi, Wang, Xin, Robson, Simon C, Wu, Yan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050864/
https://ncbi.nlm.nih.gov/pubmed/21390184
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