HAMLET Binding to α-Actinin Facilitates Tumor Cell Detachment

Cell adhesion is tightly regulated by specific molecular interactions and detachment from the extracellular matrix modifies proliferation and survival. HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) is a protein-lipid complex with tumoricidal activity that also triggers tumor cell detac...

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Autores principales: Trulsson, Maria, Yu, Hao, Gisselsson, Lennart, Chao, Yinxia, Urbano, Alexander, Aits, Sonja, Mossberg, Ann-Kristin, Svanborg, Catharina
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050841/
https://ncbi.nlm.nih.gov/pubmed/21408150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017179
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