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Changes in Proteasome Structure and Function Caused by HAMLET in Tumor Cells
BACKGROUND: Proteasomes control the level of endogenous unfolded proteins by degrading them in the proteolytic core. Insufficient degradation due to altered protein structure or proteasome inhibition may trigger cell death. This study examined the proteasome response to HAMLET, a partially unfolded...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2664966/ https://ncbi.nlm.nih.gov/pubmed/19365565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005229 |
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