Conserved features of cancer cells define their sensitivity of HAMLET-induced death; c-Myc and glycolysis

HAMLET is the first member of a new family of tumoricidal protein-lipid complexes that kill cancer cells broadly, while sparing healthy, differentiated cells. Many and diverse tumor cell types are sensitive to the lethal effect, suggesting that HAMLET identifies and activates conserved death pathway...

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Detalhes bibliográficos
Main Authors: Storm, Petter, Puthia, Manoj Kumar, Aits, Sonja, Urbano, Alexander, Northen, Trent, Powers, Scott, Bowen, Ben, Chao, Yinxia, Reindl, Wolfgang, Lee, Do Yup, Sullivan, Nancy Liu, Zhang, Jianping, Trulsson, Maria, Yang, Henry, Watson, James, Svanborg, Catharina
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041205/
https://ncbi.nlm.nih.gov/pubmed/21643007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.196
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