A Unifying Mechanism for Cancer Cell Death through Ion Channel Activation by HAMLET

Ion channels and ion fluxes control many aspects of tissue homeostasis. During oncogenic transformation, critical ion channel functions may be perturbed but conserved tumor specific ion fluxes remain to be defined. Here we used the tumoricidal protein-lipid complex HAMLET as a probe to identify ion...

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Detalhes bibliográficos
Main Authors: Storm, Petter, Kjaer Klausen, Thomas, Trulsson, Maria, Ho CS, James, Dosnon, Marion, Westergren, Tomas, Chao, Yinxia, Rydström, Anna, Yang, Henry, Pedersen, Stine Falsig, Svanborg, Catharina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591364/
https://ncbi.nlm.nih.gov/pubmed/23505537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058578
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