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HAMLET Interacts with Lipid Membranes and Perturbs Their Structure and Integrity

BACKGROUND: Cell membrane interactions rely on lipid bilayer constituents and molecules inserted within the membrane, including specific receptors. HAMLET (human α-lactalbumin made lethal to tumor cells) is a tumoricidal complex of partially unfolded α-lactalbumin (HLA) and oleic acid that is intern...

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Autori principali: Mossberg, Ann-Kristin, Puchades, Maja, Halskau, Øyvind, Baumann, Anne, Lanekoff, Ingela, Chao, Yinxia, Martinez, Aurora, Svanborg, Catharina, Karlsson, Roger
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826418/
https://ncbi.nlm.nih.gov/pubmed/20186341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009384
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