Lipids as cofactors in protein folding: Stereo-specific lipid–protein interactions are required to form HAMLET (human α-lactalbumin made lethal to tumor cells)

Proteins can adjust their structure and function in response to shifting environments. Functional diversity is created not only by the sequence but by changes in tertiary structure. Here we present evidence that lipid cofactors may enable otherwise unstable protein folding variants to maintain their...

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Autores principales: Svensson, Malin, Mossberg, Ann-Kristin, Pettersson, Jenny, Linse, Sara, Svanborg, Catharina
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2003
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366988/
https://ncbi.nlm.nih.gov/pubmed/14627740
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