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Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo
Fibrillar amyloid β (fAβ) peptide is the major component of Aβ plaques in the brains of Alzheimer's disease (AD) patients. Inflammatory mediators have previously been proposed to be drivers of Aβ pathology in AD patients by increasing amyloidogenic processing of APP and promoting Aβ accumulatio...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3050766/ https://ncbi.nlm.nih.gov/pubmed/21324189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-16 |
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