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Neuroprotection by dimethyloxalylglycine following permanent and transient focal cerebral ischemia in rats
Dimethyloxalylglycine (DMOG) is an inhibitor of prolyl-4-hydroxylase domain (PHD) enzymes that regulate the stability of hypoxia-inducible factor (HIF). We investigated the effect of DMOG on the outcome after permanent and transient middle cerebral artery occlusion (p/tMCAO) in the rat. Before and a...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3049478/ https://ncbi.nlm.nih.gov/pubmed/20407463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.60 |
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