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Inducible SUMO modification of TANK alleviates its repression of TLR7 signalling
Adaptor proteins allow temporal and spatial coordination of signalling. In this study, we show SUMOylation of the adaptor protein TANK and its interacting kinase TANK-binding kinase 1 (TBK1). Modification of TANK by the small ubiquitin-related modifier (SUMO) at the evolutionarily conserved Lys 282...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3049432/ https://ncbi.nlm.nih.gov/pubmed/21212807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.207 |
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