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Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells
HSCs either self-renew or differentiate to give rise to multipotent cells whose progeny provide blood cell precursors. However, surprisingly little is known about the factors that regulate this choice of self-renewal versus differentiation. One candidate is the Notch signaling pathway, with ex vivo...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3049401/ https://ncbi.nlm.nih.gov/pubmed/21285514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43868 |
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