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IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway
Fluid and HCO(3)(–) secretion are fundamental functions of epithelia and determine bodily fluid volume and ionic composition, among other things. Secretion of ductal fluid and HCO(3)(–) in secretory glands is fueled by Na(+)/HCO(3)(–) cotransport mediated by basolateral solute carrier family 4 membe...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3049373/ https://ncbi.nlm.nih.gov/pubmed/21317537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43475 |
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