IRBIT coordinates epithelial fluid and HCO(3)(–) secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct

Fluid and HCO(3)(–) secretion are vital functions of secretory epithelia. In most epithelia, this entails HCO(3)(–) entry at the basolateral membrane, mediated by the Na(+)-HCO(3)(–) cotransporter, pNBC1, and exit at the luminal membrane, mediated by a CFTR-SLC26 transporters complex. Here we report...

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Bibliografiset tiedot
Päätekijät: Yang, Dongki, Shcheynikov, Nikolay, Zeng, Weizhong, Ohana, Ehud, So, Insuk, Ando, Hideaki, Mizutani, Akihiro, Mikoshiba, Katsuhiko, Muallem, Shmuel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2008
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613461/
https://ncbi.nlm.nih.gov/pubmed/19033647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36983
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