IRBIT coordinates epithelial fluid and HCO(3)(–) secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct

Fluid and HCO(3)(–) secretion are vital functions of secretory epithelia. In most epithelia, this entails HCO(3)(–) entry at the basolateral membrane, mediated by the Na(+)-HCO(3)(–) cotransporter, pNBC1, and exit at the luminal membrane, mediated by a CFTR-SLC26 transporters complex. Here we report...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Yang, Dongki, Shcheynikov, Nikolay, Zeng, Weizhong, Ohana, Ehud, So, Insuk, Ando, Hideaki, Mizutani, Akihiro, Mikoshiba, Katsuhiko, Muallem, Shmuel
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613461/
https://ncbi.nlm.nih.gov/pubmed/19033647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36983
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares