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Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle
Muscular dystrophies (MDs) comprise a group of degenerative muscle disorders characterized by progressive muscle wasting and often premature death. The primary defect common to most MDs involves disruption of the dystrophin-glycoprotein complex (DGC). This leads to sarcolemmal instability and Ca(2+)...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3049367/ https://ncbi.nlm.nih.gov/pubmed/21285509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43844 |
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