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Lens induction requires attenuation of ERK signaling by Nf1

Aphakia (lack of lens) is a rare human congenital disorder with its genetic etiology largely unknown. Even in model organisms, very few mutations are known to result in such a drastic ocular defect. In this study, we have shown that homozygous deletion of Nf1, the Ras GTPase gene underlying human ne...

詳細記述

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書誌詳細
主要な著者: Carbe, Christian, Zhang, Xin
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049355/
https://ncbi.nlm.nih.gov/pubmed/21233129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr014
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