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Lens induction requires attenuation of ERK signaling by Nf1
Aphakia (lack of lens) is a rare human congenital disorder with its genetic etiology largely unknown. Even in model organisms, very few mutations are known to result in such a drastic ocular defect. In this study, we have shown that homozygous deletion of Nf1, the Ras GTPase gene underlying human ne...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3049355/ https://ncbi.nlm.nih.gov/pubmed/21233129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr014 |
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