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CAG-Repeat Length and the Age of Onset in Huntington Disease (HD): A Review and Validation Study of Statistical Approaches

BACKGROUND: CAG-repeat length in the gene for HD is inversely correlated with age of onset (AOO). A number of statistical models elucidating the relationship between CAG length and AOO have recently been published. In the present article, we review the published formulae, summarize essential differe...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Langbehn, Douglas R., Hayden, Michael, Paulsen, Jane S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048807/
https://ncbi.nlm.nih.gov/pubmed/19548255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.30992
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