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CAG Repeat Not Polyglutamine Length Determines Timing of Huntington’s Disease Onset

Variable, glutamine-encoding, CAA interruptions indicate that a property of the uninterrupted HTT CAG repeat sequence, distinct from the length of huntingtin’s polyglutamine segment, dictates the rate at which Huntington’s disease (HD) develops. The timing of onset shows no significant association w...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cell Press 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700281/
https://ncbi.nlm.nih.gov/pubmed/31398342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.06.036
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