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CAG Repeat Not Polyglutamine Length Determines Timing of Huntington’s Disease Onset
Variable, glutamine-encoding, CAA interruptions indicate that a property of the uninterrupted HTT CAG repeat sequence, distinct from the length of huntingtin’s polyglutamine segment, dictates the rate at which Huntington’s disease (HD) develops. The timing of onset shows no significant association w...
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| Published in: | Cell |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cell Press
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6700281/ https://ncbi.nlm.nih.gov/pubmed/31398342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.06.036 |
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