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Molecular Evolution, Mutation Size and Gene Pleiotropy: A Geometric Reexamination
The influence of phenotypic effects of genetic mutations on molecular evolution is not well understood. Neutral and nearly neutral theories of molecular evolution predict a negative relationship between the evolutionary rate of proteins and their functional importance; nevertheless empirical studies...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Genetics Society of America
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048784/ https://ncbi.nlm.nih.gov/pubmed/21196522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.125195 |
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