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Molecular Evolution, Mutation Size and Gene Pleiotropy: A Geometric Reexamination

The influence of phenotypic effects of genetic mutations on molecular evolution is not well understood. Neutral and nearly neutral theories of molecular evolution predict a negative relationship between the evolutionary rate of proteins and their functional importance; nevertheless empirical studies...

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Detalhes bibliográficos
Main Authors: Razeto-Barry, Pablo, Díaz, Javier, Cotoras, Darko, Vásquez, Rodrigo A.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048784/
https://ncbi.nlm.nih.gov/pubmed/21196522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.125195
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