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Evolutionary Framework for Protein Sequence Evolution and Gene Pleiotropy
In this article, we develop an evolutionary model for protein sequence evolution. Gene pleiotropy is characterized by K distinct but correlated components (molecular phenotypes) that affect the organismal fitness. These K molecular phenotypes are under stabilizing selection with microadaptation (SM)...
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| Médium: | Artigo |
| Jazyk: | Inglês |
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Copyright © 2007 by the Genetics Society of America
2007
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855142/ https://ncbi.nlm.nih.gov/pubmed/17277368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.066530 |
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