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Gene Functional Trade-Offs and the Evolution of Pleiotropy

Pleiotropy is the property of genes affecting multiple functions or characters of an organism. Genes vary widely in their degree of pleiotropy, but this variation is often considered a by-product of their evolutionary history. We present a functional theory of how pleiotropy may itself evolve. We co...

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Bibliographic Details
Main Authors: Guillaume, Frédéric, Otto, Sarah P.
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512146/
https://ncbi.nlm.nih.gov/pubmed/22982578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.143214
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