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Gene Functional Trade-Offs and the Evolution of Pleiotropy

Pleiotropy is the property of genes affecting multiple functions or characters of an organism. Genes vary widely in their degree of pleiotropy, but this variation is often considered a by-product of their evolutionary history. We present a functional theory of how pleiotropy may itself evolve. We co...

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Autors principals: Guillaume, Frédéric, Otto, Sarah P.
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512146/
https://ncbi.nlm.nih.gov/pubmed/22982578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.143214
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