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Evolutionary Framework for Protein Sequence Evolution and Gene Pleiotropy
In this article, we develop an evolutionary model for protein sequence evolution. Gene pleiotropy is characterized by K distinct but correlated components (molecular phenotypes) that affect the organismal fitness. These K molecular phenotypes are under stabilizing selection with microadaptation (SM)...
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| Κύριος συγγραφέας: | |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Copyright © 2007 by the Genetics Society of America
2007
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855142/ https://ncbi.nlm.nih.gov/pubmed/17277368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.066530 |
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