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FoxO1 and SIRT1 Regulate β-Cell Responses to Nitric Oxide

For many cell types, including pancreatic β-cells, nitric oxide is a mediator of cell death; paradoxically, nitric oxide can also activate pathways that promote the repair of cellular damage. In this report, a role for FoxO1-dependent transcriptional activation and its regulation by SIRT1 in determi...

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Autors principals: Hughes, Katherine J., Meares, Gordon P., Hansen, Polly A., Corbett, John A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048718/
https://ncbi.nlm.nih.gov/pubmed/21196578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.204768
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