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FoxO1 Mediates an Autofeedback Loop Regulating SIRT1 Expression
Forkhead transcription factor FoxO1 and the NAD(+)-dependent histone deacetylase SIRT1 are evolutionarily conserved regulators of the development of aging, oxidative stress resistance, insulin resistance, and metabolism in species ranging from invertebrates to mammals. SIRT1 deacetylates FoxO1 and e...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Biochemistry and Molecular Biology
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3037641/ https://ncbi.nlm.nih.gov/pubmed/21149440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.163667 |
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