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Repair of Nitric Oxide-damaged DNA in β-Cells Requires JNK-dependent GADD45α Expression
Proinflammatory cytokines induce nitric oxide-dependent DNA damage and ultimately β-cell death. Not only does nitric oxide cause β-cell damage, it also activates a functional repair process. In this study, the mechanisms activated by nitric oxide that facilitate the repair of damaged β-cell DNA are...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785669/ https://ncbi.nlm.nih.gov/pubmed/19648647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.046912 |
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