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PIASy Inhibits Virus-induced and Interferon-stimulated Transcription through Distinct Mechanisms
The protein inhibitor of activated STAT (PIAS) family proteins regulates innate immune responses by controlling transcription induced by Toll-like receptor, RIG-I-like receptor signaling, and JAK/STAT pathways. Here, we show that PIASy negatively regulates type I interferon (IFN) transcription. Viru...
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| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048703/ https://ncbi.nlm.nih.gov/pubmed/21199872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.195255 |
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