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Distortion of tRNA upon Near-cognate Codon Recognition on the Ribosome

The accurate decoding of the genetic information by the ribosome relies on the communication between the decoding center of the ribosome, where the tRNA anticodon interacts with the codon, and the GTPase center of EF-Tu, where GTP hydrolysis takes place. In the A/T state of decoding, the tRNA underg...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mittelstaet, Joerg, Konevega, Andrey L., Rodnina, Marina V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048702/
https://ncbi.nlm.nih.gov/pubmed/21212264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.210021
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