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Thermodynamics of the GTP-GDP-operated Conformational Switch of Selenocysteine-specific Translation Factor SelB

SelB is a specialized translation factor that binds GTP and GDP and delivers selenocysteyl-tRNA (Sec-tRNA(Sec)) to the ribosome. By analogy to elongation factor Tu (EF-Tu), SelB is expected to control the delivery and release of Sec-tRNA(Sec) to the ribosome by the structural switch between GTP- and...

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Bibliographische Detailangaben
Hauptverfasser: Paleskava, Alena, Konevega, Andrey L., Rodnina, Marina V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431659/
https://ncbi.nlm.nih.gov/pubmed/22740700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.366120
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