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Evolutionary optimization of speed and accuracy of decoding on the ribosome

Speed and accuracy of protein synthesis are fundamental parameters for the fitness of living cells, the quality control of translation, and the evolution of ribosomes. The ribosome developed complex mechanisms that allow for a uniform recognition and selection of any cognate aminoacyl-tRNA (aa-tRNA)...

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Detalhes bibliográficos
Main Authors: Wohlgemuth, Ingo, Pohl, Corinna, Mittelstaet, Joerg, Konevega, Andrey L., Rodnina, Marina V.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158919/
https://ncbi.nlm.nih.gov/pubmed/21930591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2011.0138
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