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Evolutionary optimization of speed and accuracy of decoding on the ribosome

Speed and accuracy of protein synthesis are fundamental parameters for the fitness of living cells, the quality control of translation, and the evolution of ribosomes. The ribosome developed complex mechanisms that allow for a uniform recognition and selection of any cognate aminoacyl-tRNA (aa-tRNA)...

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Hlavní autoři: Wohlgemuth, Ingo, Pohl, Corinna, Mittelstaet, Joerg, Konevega, Andrey L., Rodnina, Marina V.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158919/
https://ncbi.nlm.nih.gov/pubmed/21930591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2011.0138
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