The Endoplasmic Reticulum Stress Sensor, ATF6α, Protects against Neurotoxin-induced Dopaminergic Neuronal Death

Oxidative stress and endoplasmic reticulum (ER) stress are thought to contribute to the pathogenesis of various neurodegenerative diseases including Parkinson disease (PD), however, the relationship between these stresses remains unclear. ATF6α is an ER-membrane-bound transcription factor that is ac...

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Main Authors: Egawa, Naohiro, Yamamoto, Keisuke, Inoue, Haruhisa, Hikawa, Rie, Nishi, Katsunori, Mori, Kazutoshi, Takahashi, Ryosuke
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Neurobiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048681/
https://ncbi.nlm.nih.gov/pubmed/21131360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.156430
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