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Expression and function of the autoimmune regulator (Aire) gene in non-thymic tissue
Educational immune tolerance to self-antigens is induced primarily in the thymus where tissue-restricted antigens (TRAs) are presented to T lymphocytes by cells of the thymic stroma – a process known as central tolerance. The expression of these TRAs is controlled in part by a transcription factor e...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048612/ https://ncbi.nlm.nih.gov/pubmed/21303359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2010.04316.x |
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