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The Autoimmune Regulator (Aire) transactivates HLA‐G gene expression in thymic epithelial cells
The Autoimmune Regulator (Aire) protein coordinates the negative selection of developing thymocytes by inducing the expression of hundreds of tissue‐specific antigens within the thymic medulla, which is also a primary site of the expression of the immune checkpoint HLA‐G molecule. Considering the im...
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| Veröffentlicht in: | Immunology |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6742766/ https://ncbi.nlm.nih.gov/pubmed/31322727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13099 |
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