Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner

BACKGROUND: Fanconi anemia (FA) is a rare autosomal recessive syndrome characterized by developmental abnormalities, progressive bone marrow failure, and predisposition to cancer. The key FA protein FANCD2 crosstalks with members of DNA damage and repair pathways that also play a role at telomeres....

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Autori principali: Lyakhovich, Alex, Ramirez, Maria Jose, Castellanos, Andres, Castella, Maria, Simons, Amanda M, Parvin, Jeffrey D, Surralles, Jordi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048478/
https://ncbi.nlm.nih.gov/pubmed/21314979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9414-2-4
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