טוען...
Insights into the conformational flexibility of Bruton's tyrosine kinase from multiple ligand complex structures
Bruton's tyrosine kinase (BTK) plays a key role in B cell receptor signaling and is considered a promising drug target for lymphoma and inflammatory diseases. We have determined the X-ray crystal structures of BTK kinase domain in complex with six inhibitors from distinct chemical classes. Five...
שמור ב:
| Main Authors: | , , , , , , , , , |
|---|---|
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Wiley Subscription Services, Inc., A Wiley Company
2011
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048427/ https://ncbi.nlm.nih.gov/pubmed/21280133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.575 |
| תגים: |
הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|