A carregar...
Insights into the conformational flexibility of Bruton's tyrosine kinase from multiple ligand complex structures
Bruton's tyrosine kinase (BTK) plays a key role in B cell receptor signaling and is considered a promising drug target for lymphoma and inflammatory diseases. We have determined the X-ray crystal structures of BTK kinase domain in complex with six inhibitors from distinct chemical classes. Five...
Na minha lista:
| Main Authors: | , , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2011
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048427/ https://ncbi.nlm.nih.gov/pubmed/21280133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.575 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|