Initial Mutations Direct Alternative Pathways of Protein Evolution

Whether evolution is erratic due to random historical details, or is repeatedly directed along similar paths by certain constraints, remains unclear. Epistasis (i.e. non-additive interaction between mutations that affect fitness) is a mechanism that can contribute to both scenarios. Epistasis can co...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Salverda, Merijn L. M., Dellus, Eynat, Gorter, Florien A., Debets, Alfons J. M., van der Oost, John, Hoekstra, Rolf F., Tawfik, Dan S., de Visser, J. Arjan G. M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048372/
https://ncbi.nlm.nih.gov/pubmed/21408208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001321
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