Initial Mutations Direct Alternative Pathways of Protein Evolution

Whether evolution is erratic due to random historical details, or is repeatedly directed along similar paths by certain constraints, remains unclear. Epistasis (i.e. non-additive interaction between mutations that affect fitness) is a mechanism that can contribute to both scenarios. Epistasis can co...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Salverda, Merijn L. M., Dellus, Eynat, Gorter, Florien A., Debets, Alfons J. M., van der Oost, John, Hoekstra, Rolf F., Tawfik, Dan S., de Visser, J. Arjan G. M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2011
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048372/
https://ncbi.nlm.nih.gov/pubmed/21408208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001321
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