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Endosome–mitochondria juxtaposition during apoptosis induced by H. pylori VacA

The vacuolating cytotoxin (VacA) is an important virulence factor of Helicobacter pylori with pleiotropic effects on mammalian cells, including the ability to trigger mitochondria-dependent apoptosis. However, the mechanism by which VacA exerts its apoptotic function is unclear. Using a genetic appr...

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Bibliografische gegevens
Hoofdauteurs: Calore, F, Genisset, C, Casellato, A, Rossato, M, Codolo, G, Esposti, MD, Scorrano, L, de Bernard, M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048310/
https://ncbi.nlm.nih.gov/pubmed/20431599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.42
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