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Endosome–mitochondria juxtaposition during apoptosis induced by H. pylori VacA

The vacuolating cytotoxin (VacA) is an important virulence factor of Helicobacter pylori with pleiotropic effects on mammalian cells, including the ability to trigger mitochondria-dependent apoptosis. However, the mechanism by which VacA exerts its apoptotic function is unclear. Using a genetic appr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Calore, F, Genisset, C, Casellato, A, Rossato, M, Codolo, G, Esposti, MD, Scorrano, L, de Bernard, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048310/
https://ncbi.nlm.nih.gov/pubmed/20431599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.42
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