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Targeting of Helicobacter pylori VacA to mitochondria

One of the major virulence factors of Helicobacter pylori is the vacuolating toxin vaca. It has been known for a long time that the toxin enters host cells by endocytosis. On the other hand there is ample evidence that vaca is able to trigger apoptosis and this effect has been attributed in part to...

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Библиографические подробности
Главные авторы: Galmiche, Antoine, Rassow, Joachim
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056105/
https://ncbi.nlm.nih.gov/pubmed/21468222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.1.6.13894
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