Endoplasmic Reticulum Stress Contributes to Helicobacter Pylori VacA-Induced Apoptosis

Vacuolating cytotoxin A (VacA) is one of the important virulence factors produced by H. pylori. VacA induces apoptotic cell death, which is potentiated by ammonia. VacA also causes cell death by mitochondrial damage, via signaling pathways that are not fully defined. Our aim was to determine whether...

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Detalhes bibliográficos
Main Authors: Akazawa, Yuko, Isomoto, Hajime, Matsushima, Kayoko, Kanda, Tsutomu, Minami, Hitomi, Yamaghchi, Naoyuki, Taura, Naota, Shiozawa, Ken, Ohnita, Ken, Takeshima, Fuminao, Nakano, Masayuki, Moss, Joel, Hirayama, Toshiya, Nakao, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862672/
https://ncbi.nlm.nih.gov/pubmed/24349255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082322
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