Endoplasmic Reticulum Stress Contributes to Helicobacter Pylori VacA-Induced Apoptosis

Vacuolating cytotoxin A (VacA) is one of the important virulence factors produced by H. pylori. VacA induces apoptotic cell death, which is potentiated by ammonia. VacA also causes cell death by mitochondrial damage, via signaling pathways that are not fully defined. Our aim was to determine whether...

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Hlavní autoři: Akazawa, Yuko, Isomoto, Hajime, Matsushima, Kayoko, Kanda, Tsutomu, Minami, Hitomi, Yamaghchi, Naoyuki, Taura, Naota, Shiozawa, Ken, Ohnita, Ken, Takeshima, Fuminao, Nakano, Masayuki, Moss, Joel, Hirayama, Toshiya, Nakao, Kazuhiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862672/
https://ncbi.nlm.nih.gov/pubmed/24349255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082322
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