HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium

BACKGROUND: Tumour stromal cells differ from its normal counterpart. We have shown that tumour endothelial cells (TECs) isolated from tumour tissues are also abnormal. Furthermore, we found that mRNAs of vascular endothelial growth factor-A (VEGF-A) and cyclooxygenase-2 (COX-2) were upregulated in T...

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Dettagli Bibliografici
Autori principali: Kurosu, T, Ohga, N, Hida, Y, Maishi, N, Akiyama, K, Kakuguchi, W, Kuroshima, T, Kondo, M, Akino, T, Totsuka, Y, Shindoh, M, Higashino, F, Hida, K
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
Soggetti:
Molecular Diagnostics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048211/
https://ncbi.nlm.nih.gov/pubmed/21285980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.20
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