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HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium
BACKGROUND: Tumour stromal cells differ from its normal counterpart. We have shown that tumour endothelial cells (TECs) isolated from tumour tissues are also abnormal. Furthermore, we found that mRNAs of vascular endothelial growth factor-A (VEGF-A) and cyclooxygenase-2 (COX-2) were upregulated in T...
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| Hauptverfasser: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048211/ https://ncbi.nlm.nih.gov/pubmed/21285980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.20 |
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