HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium

BACKGROUND: Tumour stromal cells differ from its normal counterpart. We have shown that tumour endothelial cells (TECs) isolated from tumour tissues are also abnormal. Furthermore, we found that mRNAs of vascular endothelial growth factor-A (VEGF-A) and cyclooxygenase-2 (COX-2) were upregulated in T...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kurosu, T, Ohga, N, Hida, Y, Maishi, N, Akiyama, K, Kakuguchi, W, Kuroshima, T, Kondo, M, Akino, T, Totsuka, Y, Shindoh, M, Higashino, F, Hida, K
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2011
Sujets:
Molecular Diagnostics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048211/
https://ncbi.nlm.nih.gov/pubmed/21285980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.20
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