HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium

BACKGROUND: Tumour stromal cells differ from its normal counterpart. We have shown that tumour endothelial cells (TECs) isolated from tumour tissues are also abnormal. Furthermore, we found that mRNAs of vascular endothelial growth factor-A (VEGF-A) and cyclooxygenase-2 (COX-2) were upregulated in T...

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Detalhes bibliográficos
Main Authors: Kurosu, T, Ohga, N, Hida, Y, Maishi, N, Akiyama, K, Kakuguchi, W, Kuroshima, T, Kondo, M, Akino, T, Totsuka, Y, Shindoh, M, Higashino, F, Hida, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048211/
https://ncbi.nlm.nih.gov/pubmed/21285980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.20
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