PACSIN 2 represses cellular migration through direct association with cyclin D1 but not its alternate splice form cyclin D1b

Cyclin D1 overexpression is a common feature of many human malignancies. Genomic deletion analysis has demonstrated a key role for cyclin D1 in cellular proliferation, angiogenesis and cellular migration. To investigate the mechanisms contributing to cyclin D1 functions, we purified cyclin D1a-assoc...

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Huvudupphovsmän: Meng, Hui, Tian, Lifeng, Zhou, Jie, Li, Zhiping, Jiao, Xuanmao, Li, Wayne W, Plomann, Markus, Xu, Zhishun, Lisanti, Michael P, Wang, Chenguang, Pestell, Richard G
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048077/
https://ncbi.nlm.nih.gov/pubmed/21200149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.1.14243
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