CYCLIN D1 INTEGRATES ESTROGEN-MEDIATED DNA DAMAGE REPAIR SIGNALING

The cyclin D1 gene encodes the regulatory subunit of a holoenyzme that phosphorylates the retinoblastoma protein (pRb) and nuclear respiratory factor (NRF1) proteins. The abundance of cyclin D1 determines estrogen-dependent gene expression in the mammary gland of mice. Using estradiol (E(2)) and an...

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Main Authors: Li, Zhiping, Chen, Ke, Jiao, Xuanmao, Wang, Chenguang, Willmarth, Nicole E., Casimiro, Mathew C., Li, Weihua, Ju, Xiaoming, Kim, Sung Hoon, Lisanti, Michael P., Katzenellenbogen, John A., Pestell, Richard G.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102655/
https://ncbi.nlm.nih.gov/pubmed/24830723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3137
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