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Context-Dependent Transformation of Adult Pancreatic Cells by Oncogenic K-Ras
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal human malignancies. To investigate the cellular origin(s) of this cancer, we determined the effect of PDAC-relevant gene mutations in distinct cell types of the adult pancreas. We show that a subpopulation of Pdx1-expressing cells is...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048064/ https://ncbi.nlm.nih.gov/pubmed/19878870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.09.027 |
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