Regulation of autophagy and chloroquine sensitivity by oncogenic RAS in vitro is context-dependent

Chloroquine (CQ) is an antimalarial drug and late-stage inhibitor of autophagy currently FDA-approved for use in the treatment of rheumatoid arthritis and other autoimmune diseases. Based primarily on its ability to inhibit autophagy, CQ and its derivative, hydroxychloroquine, are currently being in...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Morgan, Michael J, Gamez, Graciela, Menke, Christina, Hernandez, Ariel, Thorburn, Jacqueline, Gidan, Freddi, Staskiewicz, Leah, Morgan, Shellie, Cummings, Christopher, Maycotte, Paola, Thorburn, Andrew
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Landes Bioscience 2014
Θέματα:
Basic Research Paper
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198365/
https://ncbi.nlm.nih.gov/pubmed/25136801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.32135
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