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Regulation of autophagy and chloroquine sensitivity by oncogenic RAS in vitro is context-dependent

Chloroquine (CQ) is an antimalarial drug and late-stage inhibitor of autophagy currently FDA-approved for use in the treatment of rheumatoid arthritis and other autoimmune diseases. Based primarily on its ability to inhibit autophagy, CQ and its derivative, hydroxychloroquine, are currently being in...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Morgan, Michael J, Gamez, Graciela, Menke, Christina, Hernandez, Ariel, Thorburn, Jacqueline, Gidan, Freddi, Staskiewicz, Leah, Morgan, Shellie, Cummings, Christopher, Maycotte, Paola, Thorburn, Andrew
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Landes Bioscience 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198365/
https://ncbi.nlm.nih.gov/pubmed/25136801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.32135
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